The caBIG® Impact
caBIG® grew out of the need to increase the speed by which scientific findings are applied to clinical solutions. Since its launch in 2004, caBIG® has expanded beyond the NCI-designated Cancer Centers and is being used by 700+ institutions in the United States and worldwide.
caBIG® assists with discovery and clinical research, biospecimen management, proteomics research, in vivo imaging, genome-wide association studies, and adaptive clinical trials. The initiative has also provided researchers with access to: 2.17M+ biospecimens, 4.76M+ online medical images, 42K+ well-annotated, cancer-oriented gene expression microarrays, and more.
Publications
Enabling Personalized Medicine through Health Information Technology
Center for Technology Innovation at Brookings – January 28, 2011
This report from the Center for Technology Innovation at Brookings outlines the challenges of enabling personalized medicine, and highlights caBIG® as a data model for overcoming these challenges by facilitating connectivity, integration, and the analysis of information.
Heading for the BIG Time
The Scientist – April 2008
Dr. Ken Buetow discusses how caBIG® was developed in response to an urgent need in cancer research to expedite the transformation of scientific findings into clinical solutions. By using caBIG® to put the right data in the right hands at the right time, physicians and researchers are working together to realize the promise of personalized medicine.
The caBIG® Pilot Phase Report 2003-2007
National Cancer Institute – November 2007
Presentations
Integrating Cancer Molecular, Clinical and Pathways Data with caBIG®
Molecular Medicine Tri-Conference – February 3–5, 2010
caBIG® Innovation Platform: Empowering the Nation's Cancer Centers (video)
2009 caBIG® Annual Meeting – July 21, 2009
Plenary Session and Panel Discussion with Leading Cancer Center Directors – Case Studies and Deployment
2009 caBIG® Annual Meeting – July 21, 2009
A Transformation in Cancer Biomedical Informatics with caBIG®: How this may influence the FDA
FDA Science Day – 2008
The cancer Biomedical Informatics Grid (caBIG®)
The First International Cancer Genome Consortium (ICGC) Scientific Workshop – November 15–17, 2008
Director's Notes
caBIG® 2010 year in review
caBIG® LINKS – December 2010
caBIG® Annual Meeting review
caBIG® LINKS – October 2010
caBIG® – Ahead of its time
caBIG® LINKS – September 2010
Evolution of the caBIG® community
caBIG® LINKS – June 2010
Trends at Bio-IT World and SAGE
caBIG® LINKS – May 2010
Why caBIG® is needed now more than ever
caBIG® LINKS – May 2009
Transitioning to the "Enterprise Phase" in the adoption of caBIG® tools and infrastructure
caBIG® LINKS – January 2008
Media Coverage
Translational Informatics Linking Research to Clinical Care a Key Focus of caBIG® 2010
GenomeWeb/BioInform – September 17, 2010
In covering the sixth caBIG® annual meeting, which attracted more than 1,100 participants, BioInform highlighted the diverse range of presentations that featured various caBIG® applications and their use within the community. Particular emphasis was placed on the caBIG® community's collaborative efforts to better connect research and clinical care through translational informatics.
(Note: A GenomeWeb subscription is required to receive the full text of this article.)
Communication, Clear Goals Among Factors Necessary to Successfully Deploy caBIG® Tools, Researchers Say
GenomeWeb/BioInform – September 17, 2010
In its continued coverage of the caBIG® annual meeting, Building a Collaborative Biomedical Network, BioInform reported on insights provided by community members who have deployed caBIG® applications and can offer useful tips to others who plan to do the same. Among the recommendations shared, key success factors included communication, the establishment of clear goals, and collaboration.
(Note: A GenomeWeb subscription is required to receive the full text of this article.)
A Conversation with Dr. Ken Buetow
The NCI Cancer Bulletin – May 2009
The Director of the NCI's Center for Biomedical Informatics and Information Technology discusses the caBIG® initiative, as part of a special issue devoted to bioinformatics. In the same issue, Dr. Buetow also discusses how the recovery act is boosting bioinformatics.
Translational Research Demands Virtual Biobanks
GenomeWeb Daily News – May 2009
As translational medicine efforts evolve, institutions are looking to build "virtual" biorepository management systems that combine open source tools from caBIG® with commercial software development and support.
Diagnostic companies developing KRAS tests likely to see first impact of comparative effectiveness, industry experts say
PharmaWire – April 2009
Comparative effectiveness research refers to the comparison of different types of treatments for the same disease. In many countries, cost is also taken into account. A KRAS diagnostic will help predict which patients with colorectal cancer are likely to respond to EGFR drugs. Both the American Society of Clinical Oncology (ASCO) and NCCN have updated their guidelines to say KRAS testing should be integrated into clinical practice to determine which patients should be treated with these drugs in colorectal cancer.
Winners of Bio-IT World's 2008 Best Practices Awards Honored
Bio-IT World – May 6, 2008
Dr. Ken Buetow, NCI Associate Director for Bioinformatics and Information Technology, was awarded the 2008 Bio-It World Editors Choice Award for the implementation of caBIG®. Read about Dr. Buetow's award winning work developing caBIG®.
'World Wide Web of cancer research' exploits human genome map
Computerworld – March 26, 2008
Computerworld discusses how caBIG® is helping to manage the vast amounts of data being generated by genomic research in the wake of the Human Genome project.
